Graduierteninstitut
Gliederung
Fachbereich Angewandte Naturwissenschaften, Graduierteninstitut, Institut für Technik, Ressourcenschonung und Energieeffizienz (TREE)
Forschungsfelder
- Charakterisierung von Biopolymeren, speziell Lignin
- Methoden: SEC, HPLC, Chemometrie
Standort
Rheinbach
Raum
K 224
Adresse
Heisenbergstraße 16
53359, Rheinbach
Telefon
+49 2241 865 9706Profil
Betreuung der Praktika
- Fundamentals of Organic Chemistry and Biochemistry
- Instrumentelle Analytik
- Makromolekulare Chemie
- Organische Chemie
- WPF Organische Chemie 2
- WPF Organische Chemie 3
- WPF Stem Cells for Bone Metabolism
Mitgliedschaften
Forschungsprojekte
Biopolymere gewinnen zunehmend an Bedeutung in vielen medizinischen und industriellen Anwendungen. Um die hohen Qualitätsanforderungen an diese Stoffe zu gewährleisten, ist eine strikte Qualitätskontrolle auf Seiten der Hersteller unabdingbar. Die Verfahren, die dabei zum Einsatz kommen, sind häufig zeitaufwändig und kostenintensiv. Im Rahmen des Projekts sollen neue Verfahren etabliert werden, die eine schnellere und kostengünstigere Analyse der Biopolymere zulassen.
Projektleitung an der H-BRS
Prof. Dr. Margit SchulzePublikationen
2022
Burger, R., Lindner, S., Rumpf, J., Do, X. T., Diehl, B. W., Rehahn, M., ... & Schulze, M. (2022). Benchtop versus high field NMR: Comparable performance found for the molecular weight determination of lignin. Journal of Pharmaceutical and Biomedical Analysis, 114649, doi.org/10.1016/j.jpba.2022.114649
Lindner, S., Burger, R., Rutledge, D. N., Do, X. T., Rumpf, J., Diehl, B. W., ... & Monakhova, Y. B. (2022). Is the Calibration Transfer of Multivariate Calibration Models between High-and Low-Field NMR Instruments Possible? A Case Study of Lignin Molecular Weight. Analytical Chemistry, 94(9), 3997-4004, doi.org/10.1021/acs.analchem.1c05125
2021
Burger, R., Rumpf, J., Do, X. T., Monakhova, Y. B., Diehl, B. W., Rehahn, M., & Schulze, M. (2021). Is NMR Combined with Multivariate Regression Applicable for the Molecular Weight Determination of Randomly Cross-Linked Polymers Such as Lignin?. ACS omega, 6(44), 29516-29524, doi.org/10.1021/acsomega.1c03574
Rumpf, J., Do, X. T., Burger, R., Monakhova, Y., & Schulze, M. (2021). Types of lignin, properties, and structural characterization techniques. In Lignin-Based Materials for Biomedical Applications (pp. 105-158). Elsevier, doi.org/10.1016/B978-0-12-820303-3.00001-1
2020
Bergs, M., Do, X. T., Rumpf, J., Kusch, P., Monakhova, Y., Konow, C., ... & Schulze, M. (2020). Comparing chemical composition and lignin structure of Miscanthus x giganteus and Miscanthus nagara harvested in autumn and spring and separated into stems and leaves. RSC Advances, 10(18), 10740-10751, doi.org/10.1039/C9RA10576J
Rumpf, J., Do, X. T., Burger, R., Monakhova, Y. B., & Schulze, M. (2020). Extraction of high-purity lignins via catalyst-free organosolv pulping from low-input crops. Biomacromolecules, 21(5), 1929-1942, doi.org/10.1021/acs.biomac.0c00123
2019
Alzagameem, A., Bergs, M., Do, X. T., Klein, S. E., Rumpf, J., Larkins, M., ... & Schulze, M. (2019). Low-input crops as lignocellulosic feedstock for second-generation biorefineries and the potential of chemometrics in biomass quality control. Applied Sciences, 9(11), 2252, doi.org/10.3390/app9112252
Alzagameem, A., Klein, S. E., Bergs, M., Do, X. T., Korte, I., Dohlen, S., ... & Schulze, M. (2019). Antimicrobial activity of lignin and lignin-derived cellulose and chitosan composites against selected pathogenic and spoilage microorganisms. Polymers, 11(4), 670, doi.org/10.3390/polym11040670
Bergs, M., Völkering, G., Kraska, T., Pude, R., Do, X. T., Kusch, P., ... & Schulze, M. (2019). Miscanthus x giganteus stem versus leaf-derived lignins differing in monolignol ratio and linkage. International journal of molecular sciences, 20(5), 1200, doi.org/10.3390/ijms20051200
Havelt, T., Brettschneider, S., Do, X. T., Korte, I., Kreyenschmidt, J., & Schmitz, M. (2019). Sustainable Extraction and Characterisation of Bioactive Compounds from Horse Chestnut Seed Coats for the Development of Bio-Based Additives. Resources, 8(2), 114, doi.org/10.3390/resources8020114
2018
Monakhova, Y. B., Diehl, B. W., Do, X. T., Schulze, M., & Witzleben, S. (2018). Novel method for the determination of average molecular weight of natural polymers based on 2D DOSY NMR and chemometrics: Example of heparin. Journal of pharmaceutical and biomedical analysis, 149, 128-132, doi.org/10.1016/j.jpba.2017.11.016