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Department of Natural Sciences

Pharmacology and Toxicology

Lecture

  • Fundamentals of pharmacokinetics: administration of drugs, absorption, distribution, metabolism, excretion , compartment models , relevant anatomy and physiology
  • Fundamentals of pharmacodynamics: interaction between drug and receptors/enzymes, dose response curves, signal transduction , relevant anatomy and physiology
  • Fundamentals of toxicology: special pharmacology relating to substance abuse, intoxications, pharmacokinetics of the most important narcotics, recalculation

Exercises

  • Fundamentals of pharmacokinetics: administration of drugs, absorption, distribution, metabolism, excretion , compartment models , relevant anatomy and physiology
  • Fundamentals of pharmacodynamics: interaction between drug and receptors/enzymes, dose response curves, signal transduction , relevant anatomy and physiology
  • Fundamentals of toxicology: special pharmacology relating to substance abuse, intoxications, pharmacokinetics of the most important narcotics, recalculation

Requirements

  • being regular student of the Bonn-Rhein-Sieg University of Applied Sciences, participating the 1st semester of the M.Sc. Biology course, the M.Sc. AQS course or the 4th semester of B.Sc. Forensic Sciences course.
  • successful attendance to the Safety Instructions (at the beginning of the practical course in April or October)!
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Assessment

Modular examination – graded
Laboratory course (lab reports): 30%
Oral examination or written final examination: 70%
The type of examination is announced at the beginning of each
semester. Both practical course and oral examination must be passed
independently.

 

Literature

  • Drug actions - Basic Principles and therapeutic aspects E. Mutschler/H. Derendorf; MedPharm Scientific Publishers (ISBN 3-88763-021-1)
  • Pharmacokinetic Processes, mathematics and applications Peter G. Welling Wiley Science (ISBN 0-471-47814-8)
  • Applied Biopharmaceutics and Pharmacokinetics L. Shargel/A.Yu; McGraw-Hill Medical Publishing Division; (ISBN-0-8385-0278-4)
  • Kojda G., Pharmakologie/Toxikologie systematisch