Fachbereich Angewandte Naturwissenschaften
Gliederung
Fachbereich Angewandte Naturwissenschaften
Forschungsfelder
- Ion Channels, Electrophysiology, Kinetic Modelling, Molecular Biology
Standort
Rheinbach
Raum
E104
Adresse
Von-Liebig-Straße 20
53359 Rheinbach
Telefon
+4922418659778Profil
Unravelling of structure/function correlates in ENaC channels
Research Methods
- Manual and Automated Whole-Cell Patch-Clamp
- Planar-Lipid Bilayers
- (Confocal) Fluorescence Microscopy
- Kinetic Modelling and Analysis of Ion Channel Function
- Mammalian Cell Culture, E. coli based Growth and Ion Flux Measurements, Cloning
Lebenslauf
11/2014-5/2018 Doctorate in Biophysics in the High Resolution Ion Channel Dynamics Group of Dr. Indra Schröder, TU Darmstadt, Germany
1/2017-6/2017 Exchange researcher at the Columbia University Medical Center (New York City, NY) in the Molecular Physiology Group of Ph.D. Henry Colecraft
6/2018-8/2023 Postdoctoral researcher in the Membrane Biophysics Group of Prof. Dr. Gerhard Thiel, TU Darmstadt, Germany
9/2023-7/2024 Postdoctoral researcher in the Neurophysiology and Neurosensory Systems Group of Prof. Dr. Bodo Laube, TU Darmstadt, Germany
8/2024-present Postdoctoral researcher in the Physiology Group of Prof. Dr. Mike Althaus, HBRS Rheinbach
Mitgliedschaften
German Biophysical Society (Deutsche Gesellschaft für Biophysik)
Publikationen
Dr. Oliver Rauh
2024
Tobias Schulze, Timon Sprave, Carolin Groebe, Jan Krumbach, Magnus Behringer, Kay Hamacher, Gerhard Thiel, Christian Grimm, Oliver Rauh:
Proton selective conductance and gating of lysosomal cation channel TMEM175.
doi:10.1101/2024.11.01.621492
BibTeX | RIS
Noel Tewes, Beatrice Kubitzki, Flandrit Bytyqi, Nikola Metko, Sebastian Mach, Gerhard Thiel, Oliver Rauh:
Mutation in pore-helix modulates interplay between filter gate and Ba2+ block in a Kcv channel pore.
doi:10.1085/jgp.202313514 PMID
BibTeX | RIS
Klara Eisenhauer, Wadim Weber, Philipp Kemp, Carolin Gebhardt, Marwan Kaufmann, Noel Tewes, Hanna Zhdanova, Alesia Tietze, Oliver Rauh, Viktor Stein:
Scaling the Functional Nanopore (FuN) Screen: Systematic Evaluation of Self-Assembling Membrane Peptides and Extension with a K+-Responsive Fluorescent Protein Sensor.
doi:10.1021/acssynbio.3c00671 PMID
BibTeX | RIS
2023
Anja J. Engel, Steffen Paech, Markus Langhans, James L. van Etten, Anna Moroni, Gerhard Thiel, Oliver Rauh:
Combination of hydrophobicity and codon usage bias determines sorting of model K+ channel protein to either mitochondria or endoplasmic reticulum.
doi:10.1111/tra.12915 PMID
BibTeX | RIS
Jan H. Krumbach, Daniel Bauer, Atiyeh Sadat Sharifzadeh, Andrea Saponaro, Rene Lautenschläger, Kristina Lange, Oliver Rauh, Dario DiFrancesco, Anna Moroni, Gerhard Thiel, Kay Hamacher:
Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.
doi:10.1085/jgp.202313364 PMID
BibTeX | RIS
2021
Timo Smit, Esther Schickel, Omid Azimzadeh, Christine von Toerne, Oliver Rauh, Sylvia Ritter, Marco Durante, Insa S. Schroeder:
A Human 3D Cardiomyocyte Risk Model to Study the Cardiotoxic Influence of X-rays and Other Noxae in Adults.
doi:10.3390/cells10102608 PMID
BibTeX | RIS
Stefano Conti Nibali, Maria Carmela Di Rosa, Oliver Rauh, Gerhard Thiel, Simona Reina, Vito de Pinto:
Cell-free electrophysiology of human VDACs incorporated into nanodiscs: An improved method.
doi:10.1016/j.bpr.2021.100002 PMID
BibTeX | RIS
Anja J. Engel, Marina Kithil, Markus Langhans, Oliver Rauh, Matea Cartolano, James L. van Etten, Anna Moroni, Gerhard Thiel:
Codon Bias Can Determine Sorting of a Potassium Channel Protein.
doi:10.3390/cells10051128 PMID
BibTeX | RIS
Laura-Marie Winterstein, Kerri Kukovetz, Ulf-Peter Hansen, Indra Schroeder, James L. van Etten, Anna Moroni, Gerhard Thiel, Oliver Rauh:
Distinct lipid bilayer compositions have general and protein-specific effects on K+ channel function.
doi:10.1085/jgp.202012731 PMID
BibTeX | RIS
2020
Kerri Kukovetz, Brigitte Hertel, Christopher R. Schvarcz, Andrea Saponaro, Mirja Manthey, Ulrike Burk, Timo Greiner, Grieg F. Steward, James L. van Etten, Anna Moroni, Gerhard Thiel, Oliver Rauh:
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
doi:10.3390/v12101107 PMID
BibTeX | RIS
Carter R. Murry, Irina V. Agarkova, Jayadri S. Ghosh, Fiona C. Fitzgerald, Roger M. Carlson, Brigitte Hertel, Kerri Kukovetz, Oliver Rauh, Gerhard Thiel, James L. van Etten:
Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae.
doi:10.3390/v12060678 PMID
BibTeX | RIS
2019
Denise Eckert, Tobias Schulze, Julian Stahl, Oliver Rauh, James L. van Etten, Brigitte Hertel, Indra Schroeder, Anna Moroni, Gerhard Thiel:
A small viral potassium ion channel with an inherent inward rectification.
doi:10.1080/19336950.2019.1605813 PMID
BibTeX | RIS
2018
O. Rauh, U. P. Hansen, D. D. Scheub, G. Thiel, I. Schroeder:
Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.
doi:10.1038/s41598-018-28751-w PMID
BibTeX | RIS
Laura-Marie Winterstein, Kerri Kukovetz, Oliver Rauh, Daniel L. Turman, Christian Braun, Anna Moroni, Indra Schroeder, Gerhard Thiel:
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers.
doi:10.1085/jgp.201711904 PMID
BibTeX | RIS
2017
Oliver Rauh, Ulf-Peter Hansen, Sebastian Mach, Andreas J. W. Hartel, Kenneth L. Shepard, Gerhard Thiel, Indra Schroeder:
Extended beta distributions open the access to fast gating in bilayer experiments-assigning the voltage-dependent gating to the selectivity filter.
doi:10.1002/1873-3468.12898 PMID
BibTeX | RIS
Andrea Saponaro, Alessandro Porro, Antonio Chaves-Sanjuan, Marco Nardini, Oliver Rauh, Gerhard Thiel, Anna Moroni:
Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
doi:10.1105/tpc.17.00375 PMID
BibTeX | RIS
Oliver Rauh, Martin Urban, Leonhard M. Henkes, Tobias Winterstein, Timo Greiner, James L. van Etten, Anna Moroni, Stefan M. Kast, Gerhard Thiel, Indra Schroeder:
Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K+ Channels.
doi:10.1021/jacs.7b01158 PMID
BibTeX | RIS
Patrick Voos, Mehtap Yazar, René Lautenschläger, Oliver Rauh, Anna Moroni, Gerhard Thiel:
The small neurotoxin apamin blocks not only small conductance Ca2+ activated K+ channels (SK type) but also the voltage dependent Kv1.3 channel.
doi:10.1007/s00249-016-1196-0 PMID
BibTeX | RIS
2015
Ulf-Peter Hansen, Oliver Rauh, Indra Schroeder:
A simple recipe for setting up the flux equations of cyclic and linear reaction schemes of ion transport with a high number of states: The arrow scheme.
doi:10.1080/19336950.2015.1120391 PMID
BibTeX | RIS
2014
Fenja Siotto, Corinna Martin, Oliver Rauh, James L. van Etten, Indra Schroeder, Anna Moroni, Gerhard Thiel:
Viruses infecting marine picoplancton encode functional potassium ion channels.
doi:10.1016/j.virol.2014.05.002 PMID
BibTeX | RIS